Wiley invites to the virtual seminar on «Protein Ubiquitination: Structural Insights and Mass Photometry Analysis,» where they will delve into the fascinating world of post-translational modification and its implications in cellular pathways. In this seminar, their expert speaker will present groundbreaking research on the cryo-EM structures of HACE1, both alone and in complex with its physiological substrate, RAC1. Through biophysical analyses, including HDX-MS and mass photometry, we will unravel the intricate regulatory mechanisms of HACE1 and shed light on its substrate recognition with specificity.
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