PhD student or Postdoc. Understanding and manipulating ubiquitin ligase specificities

The research group Ubiquitin Signaling Specificity (Dr. Sonja Lorenz) at the Max Planck Institute for Multidisciplinary Sciences (Germany) invites applications for the position as PhD student or Postdoc (f/m/d) in the project ‘Understanding and manipulating ubiquitin ligase specificities’. They offer a PhD or Postdoc position to explore one of the following research directions:

•  The mechanism, specificity, and consequences of cellular small-molecule ubiquitination, building on our recent discovery that drug-like compounds are selectively ubiquitinated by human HUWE1.
•  The structural mechanism and biological functions of TKUL, a dual functional kinase-ligase we identified as a novel virulence factor in Leishmani.
• Structural analyses of localization-dependent ubiquitination, combining cell-based analyses with cryo-EM/cryo-ET